A woman from Licking had to be flown to University Hospital in Columbia after being seriously hurt in an accident on Interstate 44 at the Pulaski-Phelps county line Saturday afternoon.
Two other people in the vehicle were taken to Phelps County Regional Medical Center for minor injuries in the crash.
According to the Missouri State Highway Patrol, Danielle M. Chambers, 23, a passenger in the 2002 Ford Taurus that struck the tractor-trailer, was flown to the Columbia hospital.
The driver, Randon C. Bailey, 19, of Rolla, and another passenger, Dustin L. Hanson, 29, of Licking, were hospitalized in Rolla.
The patrol stated none of the occupants were wearing seat belts.
According to the patrol, the Taurus was traveling eastbound on I-44 at mile marker 169.4 and as it changed lanes, it struck a 2011 Kenworth tractor-trailer driven by Terry W. Strickland, 54, of Claremore, Okla. The Taurus went off the left side of the road, struck a cable median barrier, returned to the interstate when it was struck on its right side by the tractor-trailer.
The Taurus then traveled off the left side of the road and struck the cable median barrier again before coming to a rest.
Strickland was not injured. He was wearing a seat belt, the patrol stated.
The Taurus was totaled and the tractor-trailer had moderate damage.
The crash was reported at 3:41 p.m.